BoardQBank CONO Part 2 Preparation | Blueprint-aligned topic distribution guide
CONO Part 2 / Clinical Sciences Examination

Topics and approximate question distribution for a 200-MCQ CONO-style exam

This page summarizes the major CONO Clinical Sciences blueprint areas, the approximate number of questions from each area, and the high-yield topics to prioritize for preparation.

1. Main 200-MCQ exam-domain breakdown

The real exam distribution is blueprint-based. Exact item counts may vary, but the following ranges are the practical planning targets for a 200-question exam.

CONO Blueprint Area Percentage of Exam Approximate Questions out of 200 Practical Study Priority
Assessment & Diagnosis 30–34% 60–68 MCQs Clinical reasoning, history, physical exam, labs, imaging, differential diagnosis, red flags, monitoring, and prognosis.
Modalities 55–59% 110–118 MCQs Highest-yield section. Focus on nutrition, botanicals, homeopathy, physical medicine, counselling, TCM/acupuncture, Chinese patent formulas, and pharmacotherapy.
Critical Care & Public Health 9–13% 18–26 MCQs Emergency recognition, referral, CPR/BLS, oxygen, infection control, biohazard safety, communicable disease reporting, and adverse reaction reporting.
Recommended 200-question mock structure: Assessment & Diagnosis 68 MCQs, Modalities 112 MCQs, and Critical Care/Public Health 20 MCQs.

2. Condition categories tested across the exam

CONO does not organize the full exam only by organ systems. The blueprint uses condition categories that cut across systems, presentations, and modalities.

Condition Category Percentage Range Approximate MCQs out of 200
Vascular9–11%18–22
Infectious9–11%18–22
Neoplastic4–6%8–12
Degenerative9–11%18–22
Inflammatory / Immunologic9–11%18–22
Congenital / Developmental6–8%12–16
Autoimmune8–10%16–20
Toxic / Environmental6–8%12–16
Traumatic4–6%8–12
Endocrine9–11%18–22
Metabolic6–8%12–16
Psychosomatic / Psychiatric9–11%18–22

3. Modalities: tested topics and practical distribution

Modalities is the largest section of the exam, representing approximately 110–118 questions out of 200. CONO does not publish an exact question number for each individual modality, so the numbers below are practical study targets.

Modality Topic What Can Be Tested Practical Target in 200-MCQ Mock
Botanical Medicine Safety, side effects, contraindications, interactions, toxicity, pharmacognosy, therapeutic effects, indications, mechanism of action, route, posology, and prescribing abbreviations. 14–16 MCQs
Homeopathy Acute prescribing, keynotes, timing, sidedness, intensity, aggravating and ameliorating factors, classical Hahnemannian prescribing, potency, and posology. 12–14 MCQs
Clinical Nutrition / Nutraceuticals / Therapeutic Diets Nutritional assessment, intake, absorption, utilization, loss, nutrient safety, side effects, contraindications, interactions, toxicity, bioavailability, food sources, macronutrients, micronutrients, and therapeutic diets. 22–24 MCQs
Physical Medicine Orthopedic tests, osseous manipulation, soft tissue manipulation, therapeutic devices, TENS, interferential current, microcurrent, light therapy, ultrasound, hydrotherapy, therapeutic exercise, and MSK prevention. 17–19 MCQs
Counselling & Health Psychology Counselling principles, lifestyle counselling, health promotion, chronic disease prevention, mind-body techniques, lifespan and developmental issues, and psychological assessment tools. 10–12 MCQs
Traditional Chinese Medicine / Acupuncture / Chinese Patent Formulas Ten questions, pulse, tongue, eight principles, vital substances, organs, meridians, five elements, Zang-Fu diagnosis, Chinese patent formula safety and prescribing, acupuncture prescription, point location, angulation, depth, clean needle technique, moxa, cupping, electro-acupuncture, and laser. 22–26 MCQs
Pharmacotherapy Pharmaceutical safety, side effects, contraindications, interactions, toxicity, therapeutic effects, indications, mechanism of action, route, and therapeutic drug monitoring. 8–12 MCQs
Highest yield

Clinical nutrition, TCM/acupuncture/Chinese patent formulas, and physical medicine.

Common question style

Case-based treatment selection, safety, contraindications, interactions, monitoring, and referral risk.

Practical total

A complete Modalities mock block should contain approximately 112–118 questions.

4. Chinese patent herbal formulas

Chinese patent herbal formulas are tested under Modalities, especially within Traditional Chinese Medicine. They may appear as direct formula questions or as case-based Zang-Fu diagnosis and safety questions.

Estimated exam weight

TCM + acupuncture + Chinese patent formulas: about 22–26 MCQs in a 200-question exam.

Chinese patent formulas alone: approximately 6–10 direct or indirect MCQs.

What is usually tested

Pattern-to-formula matching, Zang-Fu diagnosis, contraindications, pregnancy caution, toxicity, herb-drug interaction risk, and wrong-formula traps.

Release the Exterior

  • Ma Huang Tang
  • Gui Zhi Tang
  • Chuan Xiong Cha Tiao San
  • Sang Ju Yin
  • Yin Qiao San

Clear Heat

  • Long Dan Xie Gan Tang

Purge

  • Ma Zi Ren Wan
  • Da Huang Fu Zi Tang

Harmonizing

  • Si Ni San
  • Xiao Yao San
  • Jia Wei Xiao Yao San

Expel Dampness

  • Ba Zheng San

Transform Phlegm

  • Er Chen Tang

Warm the Interior

  • Si Ni Tang
  • Dang Gui Si Ni Tang

Tonify Qi

  • Bu Zhong Yi Qi Tang
  • Si Jun Zi Tang

Tonify Blood

  • Si Wu Tang

Tonify Qi and Blood

  • Ba Zhen Tang
  • Gui Pi Tang

Nourish and Tonify Yin

  • Liu Wei Di Huang Tang
  • Zuo Gui Yin
  • Da Bu Yin Wan
  • Zhi Bai Di Huang Tang

Tonify Yang

  • You Gui Wan
  • Jin Gui Shen Qi Wan

Regulate Qi

  • Ban Xia Hou Po Tang
  • Ding Chuan Tang

Warm Menses / Dispel Blood Stagnation

  • Sheng Hua Tang
  • Gui Zhi Fu Ling Wan

Nourish Heart / Calm Spirit

  • Suan Zao Ren Tang
  • Tian Wang Bu Xin Dan
  • Gan Mai Da Zao Tang

Release Wind from Skin and Channels

  • Xiao Feng San

Extinguish Internal Wind

  • Tian Ma Gou Teng Yin
Important exam traps: Ma Huang Tang versus Gui Zhi Tang, Xiao Yao San versus Jia Wei Xiao Yao San, Liu Wei Di Huang Tang versus Zhi Bai Di Huang Tang, and formulas requiring caution in pregnancy, cardiovascular disease, or significant drug interaction risk.

5. Assessment & Diagnosis: tested topics

This section is about clinical reasoning: history, physical examination, lab selection, imaging selection, differential diagnosis, red flags, prognosis, complications, and monitoring.

Tested Area What CONO Can Ask Approximate MCQs in 200-Question Exam
Patient evaluationMedical history, psychosocial history, ethical doctor-patient interaction, and physical examination.12–16
Lab testingSelect appropriate lab tests, collect and prepare specimens, interpret lab results, and identify factors interfering with labs.12–16
Imaging studiesSelect imaging, interpret basic imaging findings, and know when imaging is urgent.6–10
Common acute and chronic conditionsRecognize signs, symptoms, risk factors, comorbidities, pathogenesis, and etiology.12–16
Differential diagnosisGenerate the most likely diagnosis and important alternative diagnoses.8–12
Prognosis, complications, monitoringPredict complications, sequelae, prognosis, and follow-up requirements.5–8
Evidence-informed practiceInterpret and critique research and apply research to patient care.3–5

Practical system distribution for a 60–68 MCQ Assessment & Diagnosis block

System / Clinical Area Approximate MCQs
Cardiovascular / Vascular6–8
Infectious Disease6–8
Endocrine / Metabolic7–9
GI / Hepatobiliary5–7
Respiratory4–6
Neurology4–6
Musculoskeletal / Rheumatology / Autoimmune6–8
Renal / GU / Reproductive5–7
Pediatrics / Developmental4–6
Psychiatric / Psychosomatic4–6
Oncology / Neoplastic Red Flags3–5
Toxic / Environmental / Trauma3–5
Highest-yield Assessment & Diagnosis focus: red flags, lab interpretation, imaging selection, differential diagnosis, acute versus chronic condition recognition, prognosis, complications, and monitoring.

6. Critical Care & Public Health: tested topics

This is the smallest section, but it is high-yield because questions often test safety, emergency recognition, immediate referral, public health reporting, and infection control.

Tested Topic What CONO Can Ask Approximate MCQs in 200-Question Exam
High-risk patientsIdentify unstable or high-risk patients.4–6
Critical conditionsRecognize emergency presentations and red flags.4–6
Referral / emergency managementDecide when to refer, call EMS, or send for urgent hospital care.3–5
CPR / BLSCardiopulmonary resuscitation principles.2–3
Oxygen administrationOxygen delivery type, oxygen flow, and patient safety.2–3
Sterilization / disinfection / universal precautionsInfection-control procedures and safe clinical practice.2–4
Biohazard managementSharps, blood or body-fluid exposure, and contaminated materials.1–3
Communicable disease counsellingIsolation, prevention, and patient counselling.2–4
Communicable disease reportingReporting to the local public health authority.2–4
Adverse reaction reportingReporting serious adverse reactions to Health Canada.1–2

High-yield clinical systems for Critical Care & Public Health

Cardiovascular / Vascular

MI, cardiac arrest, hypertensive crisis, stroke/TIA, pulmonary embolism, and DVT.

Respiratory

Severe asthma, anaphylaxis, hypoxia, and respiratory distress.

Infectious Disease

Sepsis, meningitis, measles, TB, and reportable infections.

Endocrine / Metabolic

Hypoglycemia, DKA, adrenal crisis, and severe electrolyte abnormality.

Neurology

Stroke, seizure, altered level of consciousness, and severe acute headache red flags.

Trauma / Toxicology

Head injury, fracture red flags, poisoning, and toxic exposure.

Pregnancy / Pediatrics

Ectopic pregnancy red flags, preeclampsia, dehydration, and safeguarding concerns.

Psychiatric / Safety

Suicide risk, violence risk, duty to protect, and mandatory reporting.

7. Best study plan from this distribution

First priority

Modalities because this section may contain more than half of the real exam.

Second priority

Assessment & Diagnosis because it tests clinical reasoning, labs, imaging, and red flags.

Third priority

Critical Care & Public Health because it is smaller but safety-focused and easy to lose marks if not reviewed.

Practice Block Recommended Number of Practice MCQs Goal
Modalities300–500Build treatment selection, contraindication, interaction, and modality safety skills.
Chinese Patent Herbal Formulas100Master Zang-Fu diagnosis, formula matching, safety, and wrong-formula traps.
Assessment & Diagnosis200–300Improve clinical reasoning, lab interpretation, imaging selection, and differential diagnosis.
Critical Care & Public Health100Strengthen emergency recognition, referral, infection control, reporting, and BLS/oxygen knowledge.
Full 200-MCQ Mock ExamsMultiple timed mocksPractice stamina, timing, blueprint balance, and review-mode learning.

References

  1. College of Naturopaths of Ontario. Clinical Sciences Examination Blueprint and Reference Guide. Toronto: CONO; 2026.
  2. College of Naturopaths of Ontario. Ontario Clinical Sciences Examination information for applicants. Toronto: CONO; accessed 2026.

This page is an original BoardQBank educational summary prepared for CONO-style exam preparation. It is not affiliated with or endorsed by the College of Naturopaths of Ontario.